Iowa vs. Iowa State Highlights Massive Week Two College Football Slate

Week two of the college football season is here, and for Iowa fans, the wait is finally over. The annual Cy-Hawk showdown between Iowa State and No. 21 Iowa headlines a loaded Saturday of action that includes the biggest matchup of the young season: No. 1 Ohio State traveling to face No. 4 Texas.

With multiple top-25 clashes and a Thursday night showdown in the Sunshine State, this weekend offers something for every college football fan. Here is your complete guide to the games that matter most.

When is the Iowa vs. Iowa State game?

The Hawkeyes host the Cyclones at 7:30 p.m. ET on Saturday, Sept. 12. The game will be broadcast on NBC, giving the rivalry a prime-time national stage. Iowa enters the matchup ranked No. 21, while Iowa State comes in unranked but hungry to reclaim bragging rights in the state.

For Iowa fans, this is the game that defines the early season. A win over their in-state rivals would provide momentum heading into Big Ten play and validate the Hawkeyes' preseason ranking.

Thursday night: Florida A&M at No. 7 Miami

The week kicks off Thursday night when Florida A&M travels to Miami for an 8 p.m. showdown on ACC Network. The Rattlers' famous Marching 100 band will put on a show, but the Hurricanes are heavy favorites to handle business on the field.

Friday night: Missouri at Kansas renews a bitter feud

Friday night features one of the most underrated rivalries in college sports when No. 23 Missouri visits Kansas at 8 p.m. on FOX. These two programs have a history so contentious that their states once fought a war. The Border War is back, and it should be must-see television.

Skip the Rutgers-Boston College snoozefest and tune into a rivalry that actually means something.

Saturday early slate: Oklahoma at Michigan headlines the noon window

The noon window on Saturday is packed with intriguing matchups, but the headliner is No. 11 Oklahoma visiting Michigan on FOX. Sooners quarterback John Mateer will face a Wolverines defense led by star cornerback Will Johnson in what should be a physical test for both teams.

Other notable noon games include No. 6 Oregon at Oklahoma State, Arizona State at No. 10 Texas A&M, and No. 16 Penn State at Temple.

Saturday afternoon: SEC battles take center stage

The 3:30 p.m. window is loaded with SEC action. No. 12 Alabama travels to Kentucky on ABC in a game that will test Crimson Tide quarterback Keelon Russell. Meanwhile, No. 3 Notre Dame hosts Rice, and No. 15 BYU welcomes Arizona.

For those keeping an eye on the playoff picture, these afternoon games could have major implications down the road.

Saturday night: Ohio State at Texas is the marquee matchup

The game everyone will be watching is No. 1 Ohio State at No. 4 Texas, kicking off at 7:30 p.m. on ABC. Buckeyes quarterback Julian Sayin faces a Longhorns defense that has championship aspirations. Texas quarterback Arch Manning will look to cement his Heisman candidacy on the biggest stage of the season.

If you prefer to avoid the hype, No. 18 Tennessee visits Georgia Tech at 7 p.m. on ESPN, and Iowa State at Iowa takes the NBC slot.

Late night: Arkansas at Utah caps off the weekend

The final game of the night features Arkansas traveling to No. 20 Utah for a 10:15 p.m. kickoff on ESPN. The Razorbacks will be flying west after a tough SEC opener, and the Utes are eager to defend their home turf.

This game also serves as a preview for Georgia, which hosts Arkansas next week in SEC play.

Complete Week Two schedule

Here is the full slate of games for Week Two, with all times Eastern:

Thursday, Sept. 10

• Florida A&M at No. 7 Miami | 8 p.m. | ACC Network

Friday, Sept. 11

• Villanova at No. 24 Louisville | 7 p.m. | ACC Network
• Norfolk State at No. 25 Virginia | 7 p.m. | ACCNX
• Richmond at NC State | 7 p.m. | ESPNU
• Rutgers at Boston College | 7:30 p.m. | ESPN2
• No. 23 Missouri at Kansas | 8 p.m. | FOX

Saturday, Sept. 12

• No. 6 Oregon at Oklahoma State | 12 p.m. | ESPN/Disney+
• Howard at No. 5 Indiana | 12 p.m. | Big Ten Network
• Arizona State at No. 10 Texas A&M | 12 p.m. | ABC
• No. 11 Oklahoma at Michigan | 12 p.m. | FOX
• No. 16 Penn State at Temple | 12 p.m. | ESPN2
• Washington State at Kansas State | 12 p.m. | TNT
• East Tennessee State at North Carolina | 12 p.m. | ACC Network
• Old Dominion at Virginia Tech | 12 p.m. | CW
• Wake Forest at Purdue | 12 p.m. | FS1
• South Florida at Army | 12 p.m. | CBSSN
• Appalachian State at East Carolina | 12 p.m. | ESPNU
• Wofford at Kent State | 12 p.m. | ESPN+
• Dickinson (PA) at Davidson | 12 p.m. | ESPN+
• Marist at Lafayette | 12:30 p.m. | ESPN+
• Western Kentucky at No. 2 Georgia | 12:45 p.m. | SEC Network
• UT Martin at West Virginia | 1 p.m. | ESPN+
• Colgate at Central Michigan | 1 p.m. | ESPN+
• Holy Cross at Miami (Ohio) | 1 p.m. | ESPN+
• Bucknell at VMI | 1:30 p.m. | ESPN+
• Stony Brook at Ball State | 2 p.m. | ESPN+
• Eastern Washington at South Dakota | 2 p.m. | ESPN+
• Duquesne at Youngstown State | 2 p.m. | ESPN+
• William & Mary at Lehigh | 2 p.m. | ESPN+
• Drake at UNI | 2 p.m. | ESPN+
• Utah Tech at Montana | 3 p.m. | ESPN+
• Rice at No. 3 Notre Dame | 3:30 p.m. | NBC
• No. 12 Alabama at Kentucky | 3:30 p.m. | ABC/Disney+
• Arizona at No. 15 BYU | 3:30 p.m. | FOX
• Utah State at No. 19 Washington | 3:30 p.m. | Big Ten Network
• Mississippi State at Minnesota | 3:30 p.m. | CBS
• Weber State at Colorado | 3:30 p.m. | ESPN+
• UCF at Pitt | 3:30 p.m. | ESPN2
• Cal at Syracuse | 3:30 p.m. | ACC Network
• Duke at Illinois | 3:30 p.m. | FS1
• Eastern Michigan at Michigan State | 3:30 p.m. | Big Ten Network
• Maryland at UConn | 3:30 p.m. | CBSSN
• UTSA at Texas State | 3:30 p.m. | CW
• UL Monroe at UAB | 3:30 p.m. | ESPN+
• Robert Morris at Akron | 3:30 p.m. | ESPN+
• Central Connecticut at Toledo | 3:30 p.m. | ESPN+
• Sacred Heart at UMass | 3:30 p.m. | ESPN+
• Wagner at James Madison | 3:30 p.m. | ESPN+
• UNLV at North Texas | 3:45 p.m. | ESPNU
• UC Davis at No. 17 SMU | 4 p.m. | ACCNX
• Northern Colorado at Wyoming | 4 p.m. | MW+
• Mercyhurst at New Mexico | 4 p.m. | MW+
• Alabama State at Troy | 4 p.m. | ESPN+
• Lamar at Idaho | 4 p.m. | ESPN+
• Delaware at Vanderbilt | 4:15 p.m. | SEC Network
• Morehead State at Austin Peay | 5 p.m. | ESPN+
• UIW at Northern Arizona | 5 p.m. | ESPN+
• Campbell at Florida | 5:30 p.m. | SECN+
• Memphis at Boise State | 6 p.m. | USA Network
• Buffalo at Florida International | 6 p.m. | ESPN+
• Jacksonville State at Ohio | 6 p.m. | ESPN+
• Gardner-Webb at Liberty | 6 p.m. | ESPN+
• North Carolina A&T at North Carolina Central | 6 p.m. | ESPN+
• San Diego at Idaho State | 6 p.m. | ESPN+
• Chattanooga at Eastern Kentucky | 6 p.m. | ESPN+
• Charleston Southern at The Citadel | 6 p.m. | ESPN+
• Franklin at Butler | 6 p.m. | ESPN+
• Furman at Mercer | 6 p.m. | ESPN+
• Monmouth at Western Michigan | 6:30 p.m. | ESPN+
• No. 18 Tennessee at Georgia Tech | 7 p.m. | ESPN
• Southern at No. 22 Houston | 7 p.m. | ESPN+
• Towson at South Carolina | 7 p.m. | SECN+
• Western Carolina at Cincinnati | 7 p.m. | ESPN+
• Bowling Green at Nebraska | 7 p.m. | FS1
• Southern Utah at Colorado State | 7 p.m. | CBSSN
• Tulsa at Sam Houston | 7 p.m. | ESPN+
• Illinois State at Northern Illinois | 7 p.m. | MW+
• South Alabama at Tulane | 7 p.m. | ESPN+
• West Georgia at Arkansas State | 7 p.m. | ESPN+
• Georgia State at Kennesaw State | 7 p.m. | ESPN+
• Middle Tennessee at Marshall | 7 p.m. | ESPN+
• Lindenwood at Missouri State | 7 p.m. | ESPN+
• Indiana State at Eastern Illinois | 7 p.m. | ESPN+
• Valparaiso at Murray State | 7 p.m. | ESPN+
• SE Missouri State at Southern Illinois | 7 p.m. | ESPN+
• Central Oklahoma at Central Arkansas | 7 p.m. | ESPN+
• North Alabama at SE Louisiana | 7 p.m. | ESPN+
• Tarleton State at McNeese | 7 p.m. | ESPN+
• UT Rio Grand Valley at Nicholls | 7 p.m. | ESPN+
• Samford at Tennessee Tech | 7 p.m. | ESPN+
• Northwestern State at East Texas A&M | 7 p.m. | ESPN+
• Arkansas Baptist at Houston Christian | 7 p.m. | ESPN+
• New Haven at South Dakota State | 7 p.m. | ESPN+
• San Diego State at UCLA | 7:15 p.m. | Big Ten Network
• Western Illinois at Wisconsin | 7:15 p.m. | Big Ten Network
• No. 1 Ohio State at No. 4 Texas | 7:30 p.m. | ABC
• Louisiana Tech at No. 8 LSU | 7:30 p.m. | SECN+
• No. 13 Texas Tech at Oregon State | 7:30 p.m. | CBS
• Iowa State at No. 21 Iowa | 7:30 p.m. | NBC
• Georgia Southern at Clemson | 7:30 p.m. | ACC Network
• Navy at Florida Atlantic | 7:30 p.m. | ESPNU
• Fordham at Coastal Carolina | 7:30 p.m. | ESPN+
• Charlotte at No. 9 Ole Miss | 7:45 p.m. | ESPN2
• Southern Miss at Auburn | 7:45 p.m. | SEC Network
• Prairie View A&M at Baylor | 8 p.m. | ESPN+
• Grambling at TCU | 8 p.m. | ESPN+
• Stephen F. Austin at Abilene Christian | 8 p.m. | ESPN+
• Texas Southern at UTEP | 9 p.m. | MW+
• Cal Poly at San Jose State | 9 p.m. | MW+
• North Dakota State at Air Force | 10 p.m. | FS1
• North Dakota at Portland State | 10 p.m. | ESPN+
• Arkansas at No. 20 Utah | 10:15 p.m. | ESPN
• Sacramento State at Fresno State | 10:30 p.m. | CBSSN
• Montana State at Nevada | 10:30 p.m. | CW
• Louisiana at No. 14 Southern California | 11 p.m. | Big Ten Network
• New Mexico State at Hawai'i | 11:59 p.m. | MW+

Why this weekend matters for Iowa football fans

The Cy-Hawk game is more than just a rivalry. It is a measuring stick for both programs and a chance for Iowa to prove it belongs among the Big Ten's elite. With a prime-time slot on NBC, the Hawkeyes will have the nation's attention.

Beyond the state rivalry, Iowa fans should keep an eye on the Ohio State-Texas game as a preview of potential playoff matchups. The winner of that game will have a significant edge in the race for a top seed.

Whether you are heading to Kinnick Stadium or watching from home, this is a weekend no Iowa football fan will want to miss.